Even if you are not a DBA do read the article in it's entirety.
(article entited "The Only Issue" dizwell's blog.)
a) Change Control by DBAs (use scripts and logs, not command-line and how I hate GUI point-and-click !)
b) Test your backup and recovery
c) Don't "assume"
d) Murphy will be Murphy ! -- really, truly everything that can go wrong does go wrong -- read the whole article !